Program Cost May Be Reimbursed by Your HSA, HRA or FSA 🎉


Naltrexone & The Sinclair Method

A revolutionary treatment for problem drinking that uses targeted naltrexone therapy, and is clinically-proven to have a 78% success rate



The Sinclair Method (TSM) is a science-based protocol for treating alcohol use disorder. It uses the medication naltrexone in a targeted dose. Over time, most people using this protocol will experience fewer alcohol cravings and less interest in drinking.

The Sinclair Method Explained

Here is a preview into one of our course videos where we explain the basics behind this method.



  • The Sinclair Method is a long-term treatment protocol and usually takes about 6-9 months
  • This method helps eliminate strong alcohol cravings or urges to drink
  • This method makes "moderate" drinking possible for most people 
  • Research shows that people have greater success when the medication is combined with a program that supports behavior and lifestyle change, like what's available in The Alcohol Freedom Program

To read more about the scientific research behind this method, visit here or read the book, The Cure for Alcoholism by Dr Roy Eskapa.


Ready to try it for yourself?


More About Naltrexone


  • Naltrexone has been approved by the FDA for treatment of alcohol use disorder since 1994.
  • Naltrexone is a safe, non-addictive and non-habit-forming medication that has very few interactions or side effects for most people.
  • Naltrexone works by blocking the endorphin reward people get from alcohol. It does not make a person sick from alcohol like Antabuse.
  • Naltrexone is only taken before the first alcoholic drink of the day. 
  • A prescription is required in most parts of the world for naltrexone.
  • When you enroll in The Alcohol Freedom Program, we'll connect you with a telemedicine physician who can prescribe the medication. 👍

How The Sinclair Method Works

The method works by dealing with alcohol use disorder on a neurological level. 🧠 We’ll break this down into a few simple steps:

Step 1

When you drink alcohol – it produces a flood of feel-good hormones in your brain, including endorphins. This is why drinking can feel so pleasurable & rewarding.

Step 2

This flood of feel-good hormones are what drive you to keep craving, drinking & over-drinking alcohol, & ultimately developing patterns of alcohol use disorder (AUD). 

Step 3

FDA-approved medications like naltrexone can block those feel-good hormones when you drink – making the experience slightly less "rewarding."

Step 4

When those feel-good hormones are blocked repeatedly over time, most people gradually & naturally experience less interest in alcohol because they're not getting the same rewarding effects from it.

Step 5

As you begin to have less interest in alcohol, this is the time to make lifestyle changes, adjust habits & cultivate new coping strategies in order to shift the behaviors associated with over-drinking. 

Step 6

People who use this approach have the option to drink in moderation & with control, or go abstinent in the future with greater ease since the cause of over-drinking has been healed on a neurological level.


Learn more about how our program has helped people just like you sustainably change drinking habits using The Sinclair Method


Learn more

Naltrexone Works Best When Combined With Support

According to the Journal of Clinical Psychopharmacology, several studies have shown that naltrexone works best when combined with behavioral support for coping and habit change. That's why we guide and support you through this in the program, at your own pace.

Thrive Member Testimonial 


How Can Naltrexone & The Sinclair Method Help Me Change My Drinking Habits?


  1. Regained control over alcohol. This means "forgetting" to drink, not being able to finish a drink, or being able to keep alcohol in the house without drinking it.
  2. Cravings for alcohol reduced or eliminated.  This means your mind can feel more "free" as you think about alcohol less often. Many people don't even realize how much they are thinking about alcohol until they go on The Sinclair Method.
  3. Choice of moderation or abstinence. It's up to you to decide what type of role you want alcohol to play in your life. Many people have a goal to drink moderately, and others quit drinking with greater ease through The Sinclair Method.

Ready to try it for yourself?


"I support The Sinclair Method because all throughout my psychiatric residency training, alcohol treatment was very all or none in regards to AA and abstinence or using medications like Antabuse or Campral, with essentially expected poor outcomes. When I learned about The Sinclair Method, it was a lightbulb moment, and I saw immediate life-changing  responses with my patients. I have been a believer since then, as this has been the only treatment where I have seen consistent and sustained positive results. It is a game-change and a life-saver."

Sulman Aziz Mirza, MD
Triple Board Certified Psychiatrist, LouCouPsych

Access Sinclair Method Success Stories

Get access to real interviews by people who have overcome problem drinking through naltrexone and The Sinclair Method


#1 Tip for The Sinclair Method

Get instant access to our most important tip for The Sinclair Method 👇

Sinclair Method Frequently Asked Questions

Have more questions about The Sinclair Method? Check out our blog post where we answer the most commonly asked questions.

Read FAQs
Since 2018, we have helped hundreds of people gain control over alcohol using The Sinclair Method.

Will you be next?

Get Started on Naltrexone & The Sinclair Method

Learn about the physician-recommended program for targeted use of naltrexone, commonly referred to as The Sinclair Method