Program Cost May Be Reimbursed by Your HSA, HRA or FSA 🎉


Does Naltrexone Prevent Alcohol Withdrawal?

May 09, 2023

DISCLAIMER: This content is not intended to be a substitute for medical advice, but is for informational purposes only. Please seek your physician's guidance regarding naltrexone for alcohol addiction.

Many people want to know if naltrexone can help prevent alcohol withdrawal, and the answer to that is that it can: however, it largely depends on how medication is taken.

Let's dive in.

What is alcohol withdrawal?

Alcohol withdrawal is a potentially serious medical condition that can occur when someone abruptly stops drinking alcohol after a period of heavy or prolonged use. Symptoms can include tremors, seizures, hallucinations, and other serious complications.

Alcohol withdrawal occurs when a person who has been regularly consuming alcohol suddenly stops or significantly reduces their alcohol intake. The development of alcohol withdrawal is a result of the body's physiological and neurochemical adaptations to chronic alcohol consumption


Naltrexone is usually prescribed for alcohol addiction in two different methods

Naltrexone can be prescribed in two primary ways:

  1. To help people who are abstinent stay abstinent as it may help with alcohol cravings and help prevent relapse. Typically naltrexone is prescribed to take daily to help manage cravings. Taking naltrexone this way does not help with alcohol withdrawal. In this scenario, naltrexone is usually introduced after a detox, or after someone has been abstinent for a period of time.

  2. To help people who are actively drinking and want to reduce their alcohol consumption over time through The Sinclair Method. Following this protocol, naltrexone is prescribed one hour before consuming alcohol, and is not taken on alcohol-free days. This method helps people gradually reduce their drinking over time, which can help them to avoid or reduce the effects of alcohol withdrawal. More on that below.

Decades of research has shown that The Sinclair Method is the most effective way to use the medication naltrexone for treatment of alcohol use disorder – this is largely due to its specific methodology and focus on targeting the underlying mechanisms of addiction which has deals with the rewarding (and therefore addiction) effects of alcohol inside of the brain.

We specialize in this treatment at Thrive Alcohol Recovery after both of our co-founders overcome alcohol addiction using this approach when nothing else had worked.


Naltrexone following The Sinclair Method may help someone reduce the effects of alcohol withdrawal

Naltrexone following The Sinclair Method may help someone reduce the effects of alcohol withdrawal as it may allow them to reduce their drinking gradually over time.

The Sinclair Method works on the principle of pharmacological extinction. By blocking the opioid receptors, naltrexone reduces the pleasurable effects of alcohol. Over time, this can lead to a process called extinction, where the brain's craving response to alcohol gradually diminishes. As a result, individuals may find themselves gradually drinking less or losing interest in alcohol altogether.

Reducing alcohol consumption gradually through The Sinclair Method can potentially help mitigate the severity of alcohol withdrawal symptoms. By gradually decreasing alcohol intake, the body has time to adjust to lower alcohol levels, reducing the intensity of withdrawal symptoms that can occur when abruptly quitting alcohol.

However, it's important to note that while The Sinclair Method and naltrexone can be effective for reducing alcohol cravings and helping individuals control their drinking, they should be used under the guidance of a healthcare professional. Alcohol withdrawal can be a serious medical condition, and it is crucial to consult with a healthcare provider who can provide appropriate support, guidance, and monitoring during the process.

If you or someone you know is experiencing alcohol withdrawal, it is important to seek medical attention immediately. A healthcare professional can provide appropriate treatment to help manage symptoms and prevent complications.


Get started with The Sinclair Method today

Our private, at-home program will guide you step-by-step through The Sinclair Method so you can find freedom from problem drinking & live your best life.